$150–300

Looking like Frank Lloyd Wright parachuted into a 300-year-old plantation and got to work, The Inn at Middleton Place (4290 Ashley River Rd., 843/556-0500, www.theinnatmiddletonplace.com, $215–285) is one of Charleston’s most unique lodgings—and not only because it’s on the grounds of the historic and beautiful Middleton Place Plantation. The four connected buildings comprising over 50 guest rooms are modern, yet deliberately blend in with the forested, neutral-colored surroundings. The spacious rooms have that same woody minimalism, with excellent fireplaces, spacious Euro-style baths, and huge, floor-to-ceiling windows overlooking the grounds and the river.

Guests also have full access to the rest of the gorgeous Middleton grounds. The only downside is that you’re a lengthy drive from the peninsula and all its attractions, restaurants, and nightlife. While those who need constant stimulation will be disappointed in the deep quietude here, nature-lovers and those in search of peace and quiet will find this almost paradise. And don’t worry about food—the excellent Middleton Place Restaurant is open for lunch and dinner.

© Jim Morekis from Moon Charleston & Savannah, 4th Edition