Panajachel ’s main street is Calle Principal. Most buses coming in to town stop at the intersection of Calle Principal and Calle Santander, which leads directly to the lakeshore. Santander is lined with a plethora of banks, shops, restaurants, hotels, and other tourist services. You’ll find that many of these don’t use street addresses. The town hall, church, market, and a few other restaurants and hotels are found a half kilometer northeast along Calle Principal from the Calle Santander junction. East of Calle Santander and running parallel is Calle Rancho Grande, which also has some accommodations. Running roughly between the two along the lakeshore is Calle del Lago.