Guatemala [1] is a somewhat challenging country for people with disabilities, as there is little in the way of public infrastructure specifically catering to the needs of travelers with disabilities. Antigua [2] might be a bit cumbersome for travelers in wheelchairs because of its cobblestone streets but nonetheless it has ramps for wheelchair access on every street corner. There are a few exceptions to the general lack of access for those with disabilities.
Guatemala City’s new public transportation system, the Transmetro, was said to offer wheelchair access as part of its innovative infrastructure. La Aurora International Airport now also features several elevators as part of its recent renovation. Modern Guatemala City hotels housed in high-rise buildings also have these amenities. For intercity travel, the best option for travelers with disabilities is to take shuttle buses.
Links:
[1] http://www.moon.com/destinations/guatemala
[2] http://www.moon.com/destinations/guatemala/antigua