Newberry [1] has a couple of very good B&Bs, especially Barklin House (1710 College St., 803/321-9155, www.barklinhouse.com [2], $85–125), with four small but delightfully furnished rooms within a beautiful Queen Anne downtown.
Another good choice is the Dewalt House (1217 Walnut St., 803/276-3954, www.thedewalthouse.com [3], $115–130) in a big, beautiful antebellum Greek Revival building, with three big, beautiful rooms to match.
For good chain accommodations in an unbeatable location, try the Hampton Inn Newberry-Opera House (1201 Nance St., 803/276-6666, $110) right across the street from, yes, the Opera House [4].
The most well-regarded restaurant downtown is Delamater’s (1117 Boyce St., 803/276-3555, www.delamaters.com [5], Mon.–Sat. 11:30 a.m.–2 p.m. and 5–10 p.m., $10–20), a short jaunt from the Opera House. They offer a tasty line of gourmet “dinner sandwiches” as well as classics like shrimp and grits.
The most hopping nightspot downtown is The Storm Cellar (1215 Boyce St., 803/405-0000, www.thecabanainc.com [6]) just around the corner, a wine and cigar bar downstairs from the Cabana Restaurant (www.thecabanainc.com [6], $10–25).
Links:
[1] http://www.moon.com/destinations/south-carolina/columbia-and-the-midlands/outside-columbia/newberry
[2] http://www.barklinhouse.com
[3] http://www.thedewalthouse.com
[4] http://www.moon.com/destinations/south-carolina/columbia-and-the-midlands/outside-columbia/newberry/newberry-opera-house
[5] http://www.delamaters.com
[6] http://www.thecabanainc.com