There’s a plethora of fishing-related lodging and RV-style camping all around the lakes—about two dozen places in all, the vast majority on Lake Marion [1]. For a comprehensive look, go to www.santeecoopercountry.org [2]. A lot of folks opt for vacation rentals on the lakes; go to www.lakemarionvacation.com [3] for more information.
A fun place to stay near the lakes is Santee State Park (251 State Park Rd., 803/854-2408, www.southcarolinaparks.com [4]). Ten well- furnished cabins are situated on a long pier over Lake Marion, with another 20 on the lake itself. While all are two-bedroom, sleeping a maximum of six, they run $80–120 depending on size. Call or go to the website far in advance to reserve a cabin. There are also 158 lakeside campsites ($16–18).
There are several primitive campgrounds along the Lake Moultrie Passage of the Palmetto Trail (www.palmettoconservation.org [5]). Remember August–December is hunting season.
Elloree has gotten quite a bit of national press for its picturesque qualities. While the exterior of the 1906 Elloree Bed and Breakfast (660 W. Hampton St., 803/897-2225, www.elloreebandb.com [6]) doesn’t provide the best architectural example in town, its rooms are particularly well-appointed. Jack and Cindy Lane offer two guest rooms: The Old Carolina Room ($109) is actually a suite, with a large and lovely sitting room, while the Angel Room ($89) is a bit smaller, though just as tastefully appointed.
Links:
[1] http://www.moon.com/destinations/south-carolina/columbia-and-the-midlands/the-santee-cooper-region/lakes-marion-and-moultrie
[2] http://www.santeecoopercountry.org
[3] http://www.lakemarionvacation.com
[4] http://www.southcarolinaparks.com
[5] http://www.palmettoconservation.org
[6] http://www.elloreebandb.com